In our recent publication in Translational Biomedicine we are demonstrating direct capture and analysis of exosomes from cell culture media - and how to fine tune the workflow.
Ketil W. Pedersen, Bente Kierulf, Ingrid Manger, Morten P. Oksvold, Alexander Vlassov, Norbert Roos, Anette Kullmann and Axl Neurauter. Direct Isolation of Exosomes from Cell Culture: simplifying Methods for Exosome Enrichment and analysis. Translational Biomedicine 2015, Vol. 6 No 2:18.